Boyer, F.D., & Ducrot, P.H. 1999 Total synthesis of the enantiomers of Aspidiotus nerii sex pheromone.. Comptes Rendus de l'Academie des Sciences Serie II Fascicule C-Chimie 2(1): 29-33.
Notes: The synthesis of all possible isomers of the female sex pheromone of Aspidiotus nerii is described using as key step an intramolecular ester enolate alkylation reaction for the formation of the cyclobutane ring with a good control of the relative configurations of the asymmetric centers. The configurations of the stereogenic centers of the natural pheromone are determined by comparison of the biological activities of the synthetic compounds with the natural pheromone.